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Related Concept Videos

Weightlessness01:01

Weightlessness

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When an object is dropped, it accelerates toward the center of the Earth. If the net external force on the object is its weight, it is said to be in free fall; that is, the only force acting on the object is gravity. Galileo was instrumental in showing that, in the absence of air resistance, all objects fall with the same acceleration g. However, when objects on the Earth fall downward, they are never truly in free fall, because there is always some upward resistance force from the air acting...
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There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
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In eukaryotic cells, transcripts made by RNA polymerase are modified and processed before exiting the nucleus. Unprocessed RNA is called precursor mRNA or pre-mRNA to distinguish it from mature mRNA.
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Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
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Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
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Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
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Related Experiment Video

Updated: Feb 11, 2026

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery
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Analysis of human microcirculation in weightlessness: Study protocol and pre-study experiments.

Nana-Yaw Bimpong-Buta1, Peter Jirak2, Bernhard Wernly2

  • 1Department of Internal Medicine, Division of Cardiology, Pulmonary Diseases, Vascular Medicine, University Hospital Düsseldorf, Düsseldorf, Germany.

Clinical Hemorheology and Microcirculation
|May 2, 2018
PubMed
Summary
This summary is machine-generated.

Weightlessness may affect the body's smallest blood vessels, the microcirculation. This study investigates microcirculation changes during parabolic flights, finding no impact from motion sickness medications.

Keywords:
Microcirculationintravital microscopyparabolic flightsidestream darkfield-imagingweightlessness

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Area of Science:

  • Space medicine
  • Physiology
  • Cardiovascular research

Background:

  • Weightlessness causes organ system alterations.
  • Microcirculation is vital for nutrient and gas exchange.
  • Microcirculation in weightlessness remains unstudied.

Purpose of the Study:

  • Investigate weightlessness effects on microcirculation.
  • Evaluate motion sickness medication influence on microcirculation.
  • Utilize parabolic flight maneuvers to simulate weightlessness.

Main Methods:

  • Sublingual intravital measurements using sidestream darkfield microscopy.
  • Assess macrocirculation parameters: heart rate, blood pressure, blood oxygenation.
  • Conduct study during parabolic flight campaign.

Main Results:

  • Pre-study experiments showed no alteration of microcirculation by dimenhydrinate or scopolamine.
  • Motion sickness therapy did not impact microcirculation in preliminary tests.

Conclusions:

  • Motion sickness therapy will be used during parabolic flights.
  • Findings may enhance understanding of microcirculation in space and on Earth.