Related Experiment Video
Updated: Feb 11, 2026

Author Spotlight: Eco-Friendly Extraction of Bioactive Compounds Using Polyol-Based Microwave-Assisted Techniques
Published on: August 23, 2024
New Polyol Syntheses
1Institut für Organische Chemie der Universität, Tammannstrasse 2, D-37077 Göttingen (Germany), Fax: (+49) 551-399660.
Abstract:
1,3,5,…︁-Polyol structures are characteristic components of polyene macrolide antibiotics such as filipin III (1). Iterative stereoselective alkylation of lithiated cyanohydrin acetonides and subsequent reductive decyanation is one possibility for the stepwise synthesis of this class of natural products characterized by a polyol framework of 1,3-diol units.
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