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Stereocontrolled Routes to Bridged Ethers by Tandem Cyclizations
Charles M Marson1, Jon Campbell1, Michael B Hursthouse2
1Department of Chemistry, University of Sheffield, Sheffield S3 7HF (UK).
Angewandte Chemie (International Ed. in English)
|May 2, 2018
Abstract:
Ring contraction of a 3,4-epoxyalcohol, then lactolization and electrophilic attack are the steps in the domino cyclization protocol for the formation of 8-oxabicyclo[3.2.1]octane systems [Eq. (a)].
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