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Published on: April 22, 2016
Bacterial Degradation of Quinoline and Derivatives-Pathways and Their Biocatalysts
Susanne Fetzner1, Barbara Tshisuaka2, Franz Lingens2
1Fachbereich Biologie der Universität, Postfach 2503, D-26111 Oldenburg (Germany), Fax.: (+49) 441-798-3250.
Abstract:
A series of interesting enzymes were discovered during investigations on the degradation of quinoline by microorganisms. These include the molybdenum-containing hydroxylases that catalyze the transformation 1→2 and the unusual 2,4-dioxygenases that catalyze the reaction 3→4. The application of the hydroxylases may even be interesting in industry, because several quinoline derivatives are used as pharmaceuticals or agrochemicals.
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