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Updated: Feb 11, 2026

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
Expression of Chirality by Achiral Coadsorbed Molecules in Chiral Monolayers Observed by STM
Steven De Feyter1, Petrus C M Grim1, Markus Rücker1
1Department of Chemistry, Laboratory of Molecular Dynamics and Spectroscopy, Katholieke Universiteit Leuven, Celestijnenlaan 200-F, BE-3001 Heverlee (Belgium), Fax: (+32) 16-327 989.
Abstract:
The supramolecular packing mode of physisorbed monolayers built up by chiral isophthalic acid derivatives and coadsorbed achiral solvent molecules was imaged at the liquid/graphite interface with scanning tunneling microscopy (STM). The picture on the right shows the submolecularly resolved STM image of an enantiomorphous domain composed of the R enantiomer of the isophthalic acid derivative studied and 1-heptanol molecules; the latter express the chirality of the monolayer. Upon adsorption a racemic mixture is separated into enantiomorphous domains.
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