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Updated: Feb 11, 2026

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Membrane Remodeling of Giant Vesicles in Response to Localized Calcium Ion Gradients
Published on: July 16, 2018
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Digitonin as a Chemical Trigger for the Selective Transformation of Giant Vesicles
Fredric M Menger1, Jason S Keiper1
1Department of Chemistry, Emory University, Atlanta, GA 30322 (USA), Fax: (+1) 404-727-6586.
Angewandte Chemie (International Ed. in English)
|May 2, 2018
Abstract:
The rupture of cationic giant vesicles (see the picture) in the presence of anionic vesicles, or the reverse, on exposure to digitonin is dependent on the respective cholesterol levels (0-50 mol%). Thus a disparate giant vesicle population can be chemically induced to release the contents from only a portion of its members.
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