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Updated: Feb 11, 2026

Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
Published on: September 29, 2016
Organic Synthesis and Biological Signal Transduction
Klaus Hinterding1, Daniel Alonso-Díaz1, Herbert Waldmann1
1Institut für Organische Chemie der Universität, Richard-Willstätter-Allee 2, D-76128 Karlsruhe (Germany), Fax: (+49) 721-608-4825.
Abstract:
The understanding of cellular communication pathways in molecular detail is an important goal of bioorganic research. The synthesis of analogues of active substances (e.g. 1) to study the regulation of muscle contraction or the specific lipid modification of representative peptides (→2) to investigate their subcellular, targeted transfer to intracellular membranes are examples of the capability of organic synthesis is in the research of biological signal transduction mechanisms.
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