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Lithistid Sponges: Star Performers or Hosts to the Stars
Carole A Bewley1, D John Faulkner2
1Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Bldg. 5, Room B135, Bethesda, MD 20892 (USA).
Abstract:
Extremely careful separation of the symbiotic bacteria from the cells of lithistid sponges has provided evidence that in the case of Theonella swinhoei the chemically diverse and biologically active metabolites, swinholide A and theopalauamide (1), are produced by symbionts. Marine sponges of the order Lithistida contain a diverse range of exotic natural products with valuable biological and pharmacological activities.
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