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Updated: Feb 11, 2026

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
Published on: April 15, 2022
Biodegradable Polymeric Materials-Not the Origin but the Chemical Structure Determines Biodegradability
Uwe Witt1, Motonori Yamamoto1, Ursula Seeliger2
1ZKT Kuntstofflaboratorium, BASF Aktiengesellschaft, D-67056, Ludwigshafen (Germany), Fax: (+49) 621-60-41766.
Abstract:
It is completely plausible that unmodified materials of natural origin, such as the native macromolecules cellulose or starch, are biodegradable. If these materials are modified then degradation may, depending on the degree of modification, be more difficult or even impossible. In the same manner synthesized macromolecules, whether from renewable or petrochemical sources, could be inert or completey biodegradable, depending on their chemical structure.
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