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Updated: Feb 11, 2026

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
Predetermined Chirality at Metal Centers
Ulrich Knof1, Alex von Zelewsky1
1Institut für Anorganische Chemie, Universität Fribourg, CH-1700 Fribourg (Switzerland), Fax: (+41) 26-300-97-38.
Abstract:
Asymmetric synthesis in coordination chemistry was described very clearly by Smirnoff in 1920, but, contrary to the development in organic chemistry, it was almost completely neglected for several decades. The interest in chirality in coordination chemistry (see the stereoview of [Ru(bpy)3 ]2+ ) has increased rapidly in recent times as a consequence of developments in several fields where chirality is important (polynuclear systems, supramolecular structures, and enantioselective catalysis). Here we show many examples of how, through the choice of ligand, the configuration of a metal center or the chirality of a helicate can be predetermined.
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