Related Experiment Videos
The Biosynthesis of Barbamide-A Radical Pathway for "Biohalogenation"?
1Institut für Organische Chemie der Universität, Am Hubland, D-97074 Würzburg (Germany), Fax: (+49) 931-888-4606.
Angewandte Chemie (International Ed. in English)
|May 2, 2018
Abstract:
A stereoselective chlorination of a methyl group and the preference of cleavage of nonactivated primary C-H bonds in one of the methyl groups with respect to a weaker tertiary C-H bond in the course of the biosynthesis of barbamide point to a surprising, new mechanism of "biohalogenation" (see schematic diagram).