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Gold Glyconanoparticles as Water-Soluble Polyvalent Models To Study Carbohydrate Interactions
Jesús M de la Fuente1, Africa G Barrientos1, Teresa C Rojas2
1Grupo de Carbohidratos Instituto de Investigaciones Químicas, CSIC Isla de la Cartuja, Américo Vespucio s/n, 41092 Sevilla (Spain) Fax: (+34) 95-448-95-63.
Abstract:
Glycosphingolipid clustering and interactions at the cell membrane can be modeled by gold glyconanoparticles prepared with biologically significant oligosaccharides. Such water-soluble gold glyconanoparticles with highly polyvalent carbohydrate displays (see picture, gray hemisphere: gold nanoparticle) have been obtained by a simple and versatile strategy.
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