Related Experiment Video
Updated: Feb 11, 2026

16:24
Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
Published on: August 2, 2012
19.3K
Towards Synthetic Adrenaline Receptors-Shape-Selective Adrenaline Recognition in Water
Michael Herm1, Oliver Molt2, Thomas Schrader2
1Dupont Wuppertal (Germany).
Angewandte Chemie (International Ed. in English)
|May 2, 2018
Abstract:
A new rationally designed receptor molecule binds adrenaline derivatives in water. Its binding pattern imitates the interplay of noncovalent interactions operating in the natural receptor. High shape selectivity is achieved for the slim dopamine skeleton, and leads to rejection of substrates with an α-substituent, such as amino acid derivatives.
More Related Videos
Related Concept Videos
Molecular Shape and Polarity
76.0K
Dipole Moment of a Molecule
76.0K
Synthetic Biology
5.6K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
5.6K
Intracellular Signaling Cascades
53.7K
Once a ligand binds to a receptor, the signal is transmitted through the membrane and into the cytoplasm. The continuation of a signal in this manner is called signal transduction. Signal transduction only occurs with cell-surface receptors, which cannot interact with most components of the cell, such as DNA. Only internal receptors can interact directly with DNA in the nucleus to initiate protein synthesis. When a ligand binds to its receptor, conformational changes occur that affect the...
53.7K
VSEPR Theory and the Basic Shapes
85.4K
Overview of VSEPR Theory
85.4K
Enzyme-linked Receptors
86.8K
Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
86.8K
Molecular Shapes
62.4K
Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.
Two regions of electron density in a diatomic...
Two regions of electron density in a diatomic...
62.4K

