Related Experiment Video
Updated: Feb 11, 2026

Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry
Published on: October 15, 2018
Rapid Access to Complex Molecular Architectures via o-Azaquinones
K C Nicolaou1, Yong-Li Zhong1, Phil S Baran1
1Department of Chemistry and The Skaggs Institute for Chemical Biology The Scripps Research Institute 10 550 North Torrey Pines Road, La Jolla, CA 92 037 (USA) Fax: (+1) 858-784-2469 and Department of Chemistry and Biochemistry University of California, San Diego 9500 Gilman Drive, La Jolla, CA 92 093 (USA).
Abstract:
A multitude of natural product like molecules such as 2 and 3 can be readily obtained from hydroxyketoamide 1. The versatile 1 is derived, via the intermediate o-azaquinone 4, from the Dess-Martin periodinane oxidation of the corresponding anilide.
More Related Videos
06:31Highly Stereoselective Synthesis of 1,6-Ketoesters Mediated by Ionic Liquids: A Three-component Reaction Enabling Rapid Access to a New Class of Low Molecular Weight Gelators
Published on: November 27, 2015
14:29Rapid In Vivo Fixation and Isolation of Translational Complexes from Eukaryotic Cells
Published on: December 25, 2021
Related Concept Videos
Molecular Models
Molecular Chaperones and Protein Folding
The...
Protein Complex Assembly
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Polymer Classification: Architecture
Kinetic Molecular Theory: Molecular Velocities, Temperature, and Kinetic Energy
Molecular Orbital Theory II