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Updated: Feb 11, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

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Cardiovascular Magnetic Resonance in Acute ST-Segment-Elevation Myocardial Infarction: Recent Advances,

Heerajnarain Bulluck1,2, Rohan Dharmakumar3,4, Andrew E Arai5

  • 1Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College London, United Kingdom (H.B., D.J.H.).

Circulation
|May 2, 2018
PubMed

Insights

New advances in cardiovascular magnetic resonance imaging help assess heart attack (myocardial infarction) size and guide new therapies. This technology offers insights into heart damage and remodeling after ST-elevation myocardial infarction, improving patient outcomes.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Mortality from ST-segment elevation myocardial infarction (MI) is decreasing, but heart failure incidence post-MI is increasing.
  • Current treatments lack effective strategies for reducing infarct size beyond primary percutaneous coronary intervention.
  • Novel cardioprotective therapies are crucial for improving outcomes in ST-elevation MI patients.

Purpose of the Study:

  • To review recent advancements in cardiovascular magnetic resonance (CMR) imaging for ST-elevation MI.
  • To discuss the role of CMR in evaluating novel cardioprotective therapies.
  • To explore the future applications of CMR in managing ST-elevation MI.

Main Methods:

  • Utilizing multiparametric mapping cardiovascular magnetic resonance imaging.
  • Assessing myocardial edema, microvascular obstruction, and intramyocardial hemorrhage.
  • Evaluating changes in the remote myocardial interstitial space.

Main Results:

  • CMR enables accurate assessment of MI size and adverse left ventricular remodeling.
  • Multiparametric mapping provides detailed insights into the pathophysiology of myocardial injury.
  • CMR is pivotal in assessing the efficacy of emerging cardioprotective treatments.

Conclusions:

  • Cardiovascular magnetic resonance imaging is a key tool for evaluating novel therapies in ST-elevation MI.
  • Advances in CMR, particularly multiparametric mapping, enhance understanding of post-MI cardiac changes.
  • Future applications of CMR hold significant promise for improving patient care and outcomes after ST-elevation MI.

Keywords:
ST elevation myocardial infarctionhemorrhagemagnetic resonance imagingpercutaneous coronary intervention

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