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Characteristics and Incidence Trends for Pediatric Inflammatory Bowel Disease in Daegu-Kyungpook Province in Korea: a
Suk Jin Hong1,2, Seung Man Cho3,2, Byung-Ho Choe4,2
1Department of Pediatrics, Daegu Catholic University School of Medicine, Daegu, Korea.
Insights
Pediatric inflammatory bowel disease (IBD) is rapidly increasing in Korea. This study details the epidemiological and clinical features of pediatric IBD in the Daegu-Kyungpook region, noting differences from Western populations.
Area of Science:
- Gastroenterology
- Pediatrics
- Epidemiology
Background:
- Inflammatory bowel disease (IBD) is a chronic condition with increasing prevalence in children.
- Limited regional pediatric IBD data exists for Korea.
- This study addresses the need for localized epidemiological and phenotypic data.
Purpose of the Study:
- To investigate the epidemiological and phenotypic characteristics of pediatric IBD.
- To analyze incidence trends and clinical features in a specific Korean region.
- To compare findings with international pediatric IBD data.
Main Methods:
- Retrospective analysis of 122 pediatric IBD patients.
- Data collected from four university hospitals in Daegu-Kyungpook province (2010-2016).
- Incidence trends and clinical characteristics (Paris classification) were examined.
Main Results:
- 122 children diagnosed with IBD (98 Crohn's disease [CD], 24 ulcerative colitis [UC]).
- Overall IBD incidence shows an increasing trend, with CD increasing significantly.
- CD predominantly affected males, with ileocolonic involvement (L3) and specific behaviors (B1); UC showed pancolonic involvement (E4).
Conclusions:
- A rapid increase in pediatric IBD cases is observed in Daegu-Kyungpook province.
- Pediatric IBD characteristics in this region present distinct features compared to Western cohorts.
- Further regional studies are warranted to understand pediatric IBD epidemiology.
Background:
Inflammatory bowel disease (IBD) is a heterogeneous chronic disease of unknown etiology. Although it is an important disease that shows a rapid increase in pediatric population, there are no pediatric studies that represent a specific region in Korea. Therefore, we studied the epidemiological and phenotypic characteristics of pediatric IBD in Daegu-Kyungpook province, Korea.
Methods:
We included 122 children with pediatric IBD initially diagnosed at one of four university hospitals in Daegu-Kyungpook province between July 2010 and June 2016. We investigated the incidence trends, and the clinical characteristics at diagnosis were compared by Paris classification.
Results:
We included 122 children: 98 with Crohn's disease (CD) and 24 with ulcerative colitis (UC). The average age at diagnosis was 13.6 years for IBD. The incidence shows an increasing trend. CD showed a significant increase, whereas UC appears to be increasing slowly. In CD, there was a significant male predominance. For disease activity sites, the most common location was L3 (77.6%), indicating ileocolonic involvement as the major type. B1 (88.8%) was the most common disease behaviors type. Perianal disease was noted in 43 patients (43.9%) and weight loss in 60 (61.2%). In UC, E4 (58.4%) was the most common disease activity site, indicating pancolonic involvement as the major type.
Conclusion:
We found that the number of pediatric patients with IBD is increasing rapidly in Daegu-Kyungpook province in Korea. Our study also revealed that the characteristics of pediatric IBD in our province differ somewhat from those of pediatric IBD in Western countries.
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