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The Dynamic DNA Demethylation during Postnatal Neuronal Development and Neural Stem Cell Differentiation

Huikang Tao1,2, Pei Xie1,2, Yuhang Cao1,2

  • 1The Children's Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China.

Stem Cells International
|May 2, 2018
PubMed
Summary

DNA demethylation, involving TET enzymes, shows dynamic patterns in mouse brain development and neural stem cell differentiation. These changes in 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine are crucial for gene regulation.

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