Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypothesis: Accept or Fail to Reject?01:17

Hypothesis: Accept or Fail to Reject?

29.6K
The outcome of any hypothesis testing leads to rejecting or not rejecting the null hypothesis. This decision is taken based on the analysis of the data, an appropriate test statistic, an appropriate confidence level, the critical values, and P-values. However, when the evidence suggests that the null hypothesis cannot be rejected, is it right to say, 'Accept' the null hypothesis?
There are two ways to indicate that the null hypothesis is not rejected. 'Accept' the null...
29.6K
Review and Preview01:10

Review and Preview

8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

11.6K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

685
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
685
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

1.1K
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.1K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

1.1K
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The outcome of pedicle screw instrumentation removal for ongoing low back pain following posterolateral lumbar fusion.

Journal of spine surgery (Hong Kong)·2016
Same author

Do bacteria play an important role in the pathogenesis of low back pain?

ANZ journal of surgery·2015
Same author

Modic (endplate) changes in the lumbar spine: bone micro-architecture and remodelling.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2014
Same author

Markers to identify a back pain patient in probable need of spinal surgery.

Australasian chiropractic & osteopathy : journal of the Chiropractic & Osteopathic College of Australasia·2007
Same author

Potential risk factors for prolonged recovery following whiplash injury.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2004

Related Experiment Video

Updated: Feb 11, 2026

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation
04:42

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation

Published on: June 26, 2018

15.2K

Failed Back Surgery Syndrome: A Review Article.

James R Daniell1,2, Orso L Osti1,2

  • 1The University of Adelaide, Adelaide, SA, Australia.

Asian Spine Journal
|May 2, 2018
PubMed
Summary

Postsurgical spine syndrome is a growing challenge. Neuromodulation offers superior pain relief compared to other treatments, but preventing poor surgical outcomes requires awareness of prognostic indicators.

Keywords:
Chronic pain managementFailed back surgery syndromeNeuromodulationPostsurgical spine syndromeRepeat spinal surgerySpinal cord stimulation

More Related Videos

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
07:27

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

161
Author Spotlight: Recent Advancements in Reoperative Foregut Surgery
04:14

Author Spotlight: Recent Advancements in Reoperative Foregut Surgery

Published on: September 22, 2023

944

Related Experiment Videos

Last Updated: Feb 11, 2026

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation
04:42

Treating Low Back Pain in Failed Back Surgery Patients with Multicolumn-lead Spinal Cord Stimulation

Published on: June 26, 2018

15.2K
Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
07:27

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome

Published on: January 23, 2026

161
Author Spotlight: Recent Advancements in Reoperative Foregut Surgery
04:14

Author Spotlight: Recent Advancements in Reoperative Foregut Surgery

Published on: September 22, 2023

944

Area of Science:

  • Neurosurgery
  • Pain Management
  • Spinal Disorders

Background:

  • Postsurgical spine syndrome is increasingly prevalent due to expanded spinal surgery indications and an aging population.
  • A multidisciplinary approach is crucial for patients not benefiting from further surgery.

Purpose of the Study:

  • To review current management strategies for postsurgical spine syndrome.
  • To highlight the efficacy of neuromodulation and the importance of identifying prognostic indicators.

Main Methods:

  • Literature review of management options for postsurgical spine syndrome.
  • Analysis of treatment outcomes for neuropathic pain, opioids, and neuromodulation.
  • Discussion of prognostic factors influencing surgical success.

Main Results:

  • Anticonvulsant medications are effective for neuropathic pain; opioids are generally not beneficial.
  • Neuromodulation with dorsal column neurostimulators shows significant superiority over conventional treatments.
  • Psychosocial factors are critical indicators for poor surgical prognosis.

Conclusions:

  • Neuromodulation is a highly effective option for managing postsurgical spine syndrome.
  • Spinal surgeons must recognize prognostic indicators, especially psychosocial overlay, for prevention.
  • A multidisciplinary approach is essential for optimizing patient care.