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Spermatogonial stem cell transplantation and male infertility: Current status and future directions

Connor M Forbes1, Ryan Flannigan2, Peter N Schlegel2

  • 1Department of Urology, University of British Columbia, Vancouver, British Columbia, Canada.

Arab Journal of Urology
|May 2, 2018
PubMed
Abstract

Keywords:
ART, assisted reproductive technologiesAllograftBMP4, bone morphogenetic protein 4Bcl6b, B-Cell CLL/Lymphoma 6BCD(24)(34), cluster of differentiation (24)(34)FGF2, Fibroblast growth factor 2FISH, fluorescence in situ hybridisationFertility preservationGDNF, glial cell line-derived neurotrophic factorICSI, intracytoplasmic sperm injectionID4, inhibitor of differentiation 4KS, Klinefelter syndromeMale infertilityNon-obstructive azoospermiaOnco-fertilityPGC, primordial germ cellsPLZF, promyelocytic leukaemia zinc fingerPRISMA, Preferred Reporting Items for Systematic Reviews and Meta-AnalysesRA(R), retinoic acid (receptor)SPG, spermatogoniaSSC, spermatogonial stem cellStem cell therapyStra8, stimulated by RA 8ZBTB, zinc finger and broad complex/Tramtrack/bric-a-bracc-Kit, KIT Proto-oncogene receptor tyrosine kinase

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