Related Experiment Video
Updated: Feb 11, 2026

Breakfast Habits among Schoolchildren in the City of Uruguaiana, Brazil
Published on: July 29, 2020
Regulation of habit formation in the dorsal striatum
Melissa Malvaez1, Kate M Wassum1,2
1Dept. of Psychology, UCLA, Los Angeles, CA 90095, USA.
Abstract:
Habits are an essential and pervasive component of our daily lives that allow us to efficiently perform routine tasks. But their disruption contributes to the symptoms that underlie many psychiatric diseases. Emerging data are revealing the cellular and molecular mechanisms of habit formation in the dorsal striatum. New data suggest that in both the dorsolateral and dorsomedial striatum histone deacetylase (HDAC) activity acts as a critical negative regulator of the transcriptional processes underlying habit formation. In this review, we discuss this recent work and draw conclusions relevant to the treatment of diseases marked by maladaptive habits.
More Related Videos
06:00Cortex-, Hippocampus-, Thalamus-, Hypothalamus-, Lateral Septal Nucleus- and Striatum-specific In Utero Electroporation in the C57BL/6 Mouse
Published on: January 18, 2016
09:48Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration
Published on: May 3, 2017
Related Concept Videos
Epigenetic Regulation
GTPases and their Regulation
Large G-proteins,...
Regulated Protein Degradation
Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...
Master Transcription Regulators
Negative Regulator Molecules
Formation of Species