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Updated: Feb 11, 2026

Psychophysiological Assessment of the Effectiveness of Emotion Regulation Strategies in Childhood
Published on: February 11, 2017
Emotion regulation and premedication success relationship in children who underwent general anesthesia
Insights
Midazolam premedication effectively reduced emergence agitation in children undergoing tonsillectomy. Children with emotion regulation difficulties experienced more anxiety and agitation post-surgery.
Area of Science:
- Pediatric Anesthesiology
- Child Psychology
Background:
- Premedication with midazolam is common in pediatric surgery.
- Understanding factors influencing anesthetic efficacy is crucial for patient care.
Purpose of the Study:
- To investigate the relationship between emotion regulation and midazolam's effectiveness.
- To assess the impact of midazolam premedication on pediatric surgical outcomes.
Main Methods:
- Sixty-three children (3-8 years) undergoing tonsillectomy received midazolam or no premedication.
- Evaluated behavioral/emotional status using CPRS-48 and ERC.
- Recorded sedation, pain, and emergence agitation using WSS, OPS, and PAED scales.
Main Results:
- Midazolam group showed significantly higher rates of sedation (90.6% vs 25.8%).
- Lower postoperative pain (OPS) and emergence agitation (PAED) scores in the midazolam group.
- Emotion regulation correlated with sedation and agitation in the no-premedication group.
Conclusions:
- Children with emotion regulation disorders exhibit increased anxiety and postoperative emergence agitation.
- Midazolam premedication significantly reduces the incidence of emergence agitation in pediatric surgical patients.
Abstract:
Background/aim: This study aims to investigate the relationship between emotion regulation characteristics and the efficacy of midazolam premedication. Materials and methods: Sixty-three children, aged 3 to 8 years old, with tonsillectomy and/or adenoidectomy and taking premedication with midazolam (Group 2) or without premedication (Group 1), were included in this study. The behavioral and emotional status of the children was evaluated with the Conners Parent Rating Scale-48 (CPRS-48) and Emotion Regulation Checklist (ERC). Age, sex, body weight, response to intravenous (IV) cannulation and mask, hemodynamic data, preoperative sedation scores [Wilton Sedation Scale (WSS)], postoperative pain intensity [Objective Pain Scale (OPS)], and emergence agitation (EA) level [Pediatric Anesthesia Emergence Delirium (PAED)] were recorded. Results: A total of 90.6% patients were quiet and sleepy in Group 2, and 25.8% in Group 1. The mean scores of OPS and PAED were higher in Group 1, and the percentage of patients with PAED score of >10 was 51.6% in Group 1 and 18.8% in Group 2 (P < 0.05). In Group 1, a significant correlation was found between PAED scores and WSS and the subfactors of the CPRS-48 (P < 0.05). A correlation was found between WSS and subfactors of ERS in Group 1 (P < 0.05). Conclusion: The incidence of anxiety and postoperative EA is increased in children with emotion regulation disorder, and midazolam premedication reduced the frequency of EA.
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