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Factors Associated with Enhanced Gross Motor Progress in Children with Cerebral Palsy: A Register-Based Study
Gunfrid V Størvold1, Reidun B Jahnsen2, Kari Anne I Evensen3
1a Habilitation Centre, Nord-Trøndelag Hospital Trust , Levanger , Norway.
Insights
Intensive training significantly improved gross motor progress in children with cerebral palsy (CP). Intellectual disability negatively impacted progress, while preventing ankle contractures is crucial for development.
Area of Science:
- Pediatrics
- Neurology
- Rehabilitation Medicine
Background:
- Cerebral palsy (CP) affects motor function in children.
- Understanding factors influencing gross motor progress is vital for targeted interventions.
Purpose of the Study:
- To investigate the relationship between interventions, child characteristics, and gross motor progress in children with CP.
- To identify key factors that promote or hinder motor development in this population.
Main Methods:
- A prospective cohort study involving 442 children (aged 2-12 years) with CP.
- Gross motor progress was assessed using repeated measures of the Gross Motor Function Measure (GMFM-66) percentiles.
- Linear mixed models analyzed the association between interventions, child characteristics, and motor progress over a mean follow-up of 2.9 years.
Main Results:
- Intensive training (≥3 sessions/week or intensive programs) was the sole intervention linked to enhanced gross motor progress (3.3 percentiles).
- Children with intellectual disability showed significantly lower gross motor function (24.2 percentiles).
- Eating problems and ankle contractures were also associated with reduced motor progress.
Conclusions:
- Intensive training positively impacts gross motor progress in children with CP over time.
- Intellectual disability is a significant negative prognostic factor for motor development.
- Preventing ankle contractures is important for optimizing gross motor progress in children with CP.
Aim:
To examine associations between interventions and child characteristics; and enhanced gross motor progress in children with cerebral palsy (CP).
Methods:
Prospective cohort study based on 2048 assessments of 442 children (256 boys, 186 girls) aged 2-12 years registered in the Cerebral Palsy Follow-up Program and the Cerebral Palsy Register of Norway. Gross motor progress estimates were based on repeated measures of reference percentiles for the Gross Motor Function Measure (GMFM-66) in a linear mixed model. Mean follow-up time: 2.9 years.
Results:
Intensive training was the only intervention factor associated with enhanced gross motor progress (mean 3.3 percentiles, 95% CI: 1.0, 5.5 per period of ≥3 sessions per week and/or participation in an intensive program). Gross motor function was on average 24.2 percentiles (95% CI: 15.2, 33.2) lower in children with intellectual disability compared with others. Except for eating problems (-10.5 percentiles 95% CI: -18.5, -2.4) and ankle contractures by age (-1.9 percentiles 95% CI: -3.6, -0.2) no other factors examined were associated with long-term gross motor progress.
Conclusions:
Intensive training was associated with enhanced gross motor progress over an average of 2.9 years in children with CP. Intellectual disability was a strong negative prognostic factor. Preventing ankle contractures appears important for gross motor progress.
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