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Related Experiment Video

Updated: Jul 28, 2026

Transabdominal Ultrasound for Pregnancy Diagnosis in Reeves' Muntjac Deer
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Rosacea fulminans during pregnancy.

A G Markou, V Alessandrini, J M Muray

    Clinical and Experimental Obstetrics & Gynecology
    |May 2, 2018
    PubMed
    Summary

    Rosacea fulminans (RF) is a severe pregnancy dermatosis. Treatment with prednisone and azithromycin showed significant improvement after delivery.

    Area of Science:

    • Dermatology
    • Obstetrics
    • Pharmacology

    Background:

    • Rosacea fulminans (RF) is a severe facial dermatosis characterized by sudden onset of pustules, papules, and erythema.
    • Treatment during pregnancy is challenging due to potential impacts on obstetrical outcomes.

    Observation:

    • A 37-year-old pregnant patient presented with RF and ocular manifestations in her fourth pregnancy at 37 weeks gestation.
    • Isotretinoin, a common RF treatment, was contraindicated.
    • Alternative treatment involved prednisone and azithromycin.

    Findings:

    • Significant improvement in RF symptoms was observed after delivery at 38 weeks gestation.
    • The patient's condition responded well to the alternative treatment regimen.

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    Implications:

    • This case highlights a successful alternative treatment approach for rosacea fulminans during late pregnancy.
    • Early postpartum improvement suggests a potential hormonal influence or resolution post-delivery.
    • Further research into RF etiology and safe, effective pregnancy treatments is warranted.