[Research and Design of Respiratory Impedance Measurement System Based on Forced Oscillation Technique]

Area of Science:

• Respiratory Physiology
• Biomedical Engineering
• Pulmonary Function Testing

Background:

• The forced oscillation technique (FOT) is an active method for assessing pulmonary function.
• It derives respiratory system mechanical characteristics using linear system identification theory.
• Accurate measurement of respiratory mechanics is crucial for diagnosing and managing lung diseases.

Purpose of the Study:

• To develop and validate a pulmonary function determination system based on the forced oscillation technique.
• To analyze critical technologies for system development, including sensor selection and signal generation.
• To evaluate the system's performance in measuring respiratory impedance.

Main Methods:

• A pulmonary function determination system was designed and built utilizing the FOT.
• Key components analyzed include oscillation air generators, pressure/flow sensors, signal design, and synchronous data sampling.
• A LabVIEW-based software program was developed for system control and data acquisition.
• System performance was verified through component testing and simulation experiments with an ASL5000 model lung.

Main Results:

• The performance of critical components like sensors and the oscillation air generator was verified.
• The driving signal amplitude was optimized based on frequency response analysis (4-40 Hz).
• Simulation experiments with the ASL5000 model lung showed results close to the model's set values for respiratory impedance.

Conclusions:

• The developed pulmonary function determination system based on FOT demonstrates sufficient performance.
• The system provides a viable tool for in-depth research into the mechanical properties of the respiratory system.
• This technology has the potential to enhance the understanding and assessment of pulmonary function.