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Cell-based therapy for the treatment of female stress urinary incontinence: an early cost-effectiveness analysis
Andreas West Vilsbøll1, Jakob Munk Mouritsen1, Line Park Jensen1
1Department of Health Science & Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Aim:
To perform an early cost-effectiveness analysis of in vitro expanded myoblasts (IVM) and minced myofibers versus midurethral slings (MUS) for surgical treatment of female stress urinary incontinence.
Methods:
Cost-effectiveness and sensitivity analyses were performed using a decision tree comprising previously published data and expert opinions.
Results & Conclusion:
In the base case scenario, MUS was the cost-effective strategy with a negative incremental cost-effectiveness ratio compared with IVM and a positive incremental cost-effectiveness ratio compared with minced myofibers. However, the sensitivity analysis indicates that IVM may become an alternative providing greater effect at a higher cost. With the possibility of becoming more effective, IVM treatment would be advantageous over MUS given its reduced invasiveness and lower risks of complications.
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