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Long-term Postoperative Nutritional Status Affects Prognosis Even After Infectious Complications in Gastric Cancer
Jun Kiuchi1, Shuhei Komatsu2, Toshiyuki Kosuga1
1Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Aim:
This study was designed to investigate the clinical impact of postoperative serum albumin level on severe postoperative complications (SPCs) and prognosis.
Materials And Methods:
Data for a total of 728 consecutive patients who underwent curative gastrectomy for gastric cancer between 2004 and 2013 were retrospectively analyzed. From these patients, a propensity score-matched analysis was performed based on 14 clinicopathological and surgical factors.
Results:
Short-term decrease in postoperative serum albumin level was not associated with the occurrence of SPCs. Regarding long-term decrease in serum albumin level, a decrease of ≥0.5 g/dl at 3 months did not affect the long-term survival of patients without SPCs, but was related to a significantly poorer prognosis in patients with SPCs. By multivariate analysis, long-term decrease of serum albumin level was an independent prognostic factor in patients with SPCs.
Conclusion:
Long-term postoperative nutritional status as shown by a low level of albumin was related to prognosis in patients with SPCs.
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