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Updated: Feb 11, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
Published on: January 17, 2025
Staphylococcus aureus colonization in an institutionalized elderly population in the Bay of Cadiz area, Spain:
María Pérez-Eslava1, Nuria López-Ruíz2, Elvira María Flores-Cebada1
1Centro de Salud Barrio Bajo, Arcos de la Frontera, Arcos de la Frontera, Cádiz, España.
Background And Objective:
Staphylococcus aureus is a health problem behind a great variety of infections. The objective of the study was to establish the prevalence and risk factors of S. aureus carriers in community nursing homes in Cadiz.
Patients And Method:
A cross study from September 2016 to May 2017.
Population:
All residents institutionalized in the largest long-term care facilities centers in Cadiz. The main variable was being a S. aureus carrier (sensitive and resistant to methicillin, MSSA and MRSA). The independent variables were age, sex, comorbidity, functional status, antibiotic therapy and hospitalization in the last three months. Bivariate analysis with logistic regression was conducted.
Results:
Prevalence of colonization: MSSA 17,4% and MRSA 3.8%. Use of beta-lactams was significantly related to a MSSA and MRSA carrier status using multivariate logistic regression OR = 3.3 and OR = 3.8.
Conclusions:
There is a low prevalence of S. aureus carriers in the study population. Use of beta-lactams before the study was significantly associated with being a carrier colonized by MSSA y MRSA. Primary care prescriptions are a key in controlling pathogenic multiresistant strains.
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