Related Experiment Video

Updated: Feb 11, 2026

A Novel High-resolution In vivo Imaging Technique to Study the Dynamic Response of Intracranial Structures to Tumor Growth and Therapeutics
12:09

A Novel High-resolution In vivo Imaging Technique to Study the Dynamic Response of Intracranial Structures to Tumor Growth and Therapeutics

Published on: June 16, 2013

12.0K

Pediatric intracranial aneurysms: changes from previous studies

Ruiqi Chen1, Si Zhang1, Chao You1

  • 1Department of Neurosurgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan, 610041, People's Republic of China.

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|May 3, 2018
PubMed

Insights

Pediatric intracranial aneurysms (PIAs) present differently by age, with middle cerebral artery involvement being common. Pseudoaneurysms and distal arterial aneurysms are notable subtypes requiring further study.

Area of Science:

  • Neurology
  • Pediatric Neurosurgery
  • Vascular Neurology

Background:

  • Pediatric intracranial aneurysms (PIAs) are rare but serious vascular malformations.
  • Understanding their unique characteristics is crucial for effective management.

Purpose of the Study:

  • To enhance understanding of pediatric intracranial aneurysms (PIAs).
  • To identify key demographic, clinical, and etiological features of PIAs.

Main Methods:

  • Retrospective analysis of 66 PIAs in 64 pediatric patients treated between January 2012 and April 2017.
  • Review of clinical data, treatment details, and follow-up outcomes.

Main Results:

  • Mean patient age was 11.4 years, with a male predominance (68.8%).
  • Seizures were common in younger children (0-5 years), while headaches predominated in older children (6-18 years).
  • Middle cerebral artery (MCA) was the most frequent location (42.4%); pseudoaneurysms (23.4%) were often linked to head trauma; distal arterial aneurysms (54.7%) correlated with seizures.

Conclusions:

  • New findings include age-specific symptoms, MCA predominance, high pseudoaneurysm rates with trauma etiology, and distal aneurysm-seizure links.
  • These insights contribute to a better understanding of PIA heterogeneity and management strategies.
Abstract

Keywords:
Distal arterial aneurysmsIntracranial aneurysmsPediatric patientsPseudoaneurysms

More Related Videos

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit06:11

Arterial Pouch Microsurgical Bifurcation Aneurysm Model in the Rabbit

Published on: May 14, 2020

2.8K
Intracranial Pharmacotherapy and Pain Assays in Rodents02:26

Intracranial Pharmacotherapy and Pain Assays in Rodents

Published on: April 9, 2019

5.9K

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
375
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
439
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
274
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
482
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
312
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
330