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Updated: Feb 11, 2026

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Structure-based working model of SecDF, a proton-driven bacterial protein translocation factor

Tomoya Tsukazaki1

  • 1Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara 630-0192, Japan.

FEMS Microbiology Letters
|May 3, 2018
PubMed
Summary

SecDF, a bacterial membrane protein, acts as an independent motor for protein translocation, utilizing proton gradients to pull precursor proteins into the periplasm. Recent structural studies reveal its dynamic molecular mechanisms.

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