Suspected Driving Under the Influence Case Involving Mitragynine

Area of Science:

• Pharmacology
• Forensic Toxicology
• Drug Enforcement

Background:

• Mitragynine (kratom) is a novel psychoactive substance (NPS) with dose-dependent stimulant and sedative effects.
• Available online, kratom has been linked to adverse effects including tachycardia, agitation, and hallucinations.

Observation:

• This case details the first suspected driving under the influence (DUI) incident involving mitragynine.
• A 37-year-old female driver, suspected of DUI after a near-collision, admitted to kratom use.
• Drug Recognition Expert (DRE) evaluation indicated central nervous system stimulant and cannabis influence.

Findings:

• Alkaline drug screen detected mitragynine qualitatively in the driver's blood.
• Blood analysis also quantified amphetamine at 0.052 mg/L.
• Mitragynine and citalopram were qualitatively identified.

Implications:

• This case underscores the potential for mitragynine to impair driving ability.
• Highlights the need for expanded drug testing protocols in DUI cases involving NPS.
• Emphasizes the public health risks associated with the increasing availability of kratom.