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Pediatric Tuina for promoting growth and development of preterm infants: A protocol for the systematic review of
Xinghe Zhang1, Taipin Guo, Bowen Zhu
1School of Acupuncture-Tuina, Shandong University of Traditional Chinese Medicine, Jinan, Shandong School of Acupuncture-Tuina and Rehabilitation, Yunnan University of Traditional Chinese Medicine, Kunming, China.
Insights
Pediatric Tuina may effectively promote growth and development in preterm infants. This systematic review evaluates its efficacy and safety as an early intervention for these vulnerable babies.
Area of Science:
- Neonatal care
- Developmental pediatrics
- Integrative medicine
Background:
- Preterm infants (born before 37 weeks) often face growth and developmental challenges.
- Early intervention is crucial to mitigate long-term disabilities in survivors.
- Pediatric Tuina has shown promise in preliminary clinical trials for preterm infants.
Purpose of the Study:
- To systematically review and evaluate the efficacy and safety of pediatric Tuina.
- To assess its role as an early intervention for promoting growth and development in preterm infants.
Main Methods:
- Comprehensive search of multiple electronic databases (Cochrane, MEDLINE, EBASE, etc.) up to April 1, 2018.
- Inclusion of all published randomized controlled trials (RCTs).
- Data retrieval, screening, quality assessment, and analysis by two independent researchers using Review Manager (V.5.3.5).
- Meta-analyses, subgroup analyses, and descriptive analyses will be conducted as data permit.
Main Results:
- Synthesis of evidence on key outcomes including weight gain, motor and neuropsychological development.
- Analysis of clinical outcomes such as length of hospital stay and time to weight recovery.
- Evaluation of respiratory support needs (days on supplemental oxygen) and sleep patterns.
- Assessment of reported side effects and safety profile.
Conclusions:
- This systematic review aims to provide robust evidence on the effectiveness of pediatric Tuina for preterm infants.
- The findings will inform clinical practice regarding the use of Tuina as an early intervention strategy.
Background:
Preterm infants are babies born alive before 37 weeks. Many survived infants concomitant with defects of growth and development, a lifetime of disability usually as following when insufficient intervention. In early intervention of preterm infants, pediatric Tuina shows good effect in many Chinese and some English clinical trials. This systematic review is aimed to evaluate the efficacy and safety of pediatric Tuina for promoting growth and development of preterm infants.
Methods:
The electronic databases of Cochrane Library, MEDLINE, EBASE, Web of Science, Springer, World Health Organization International Clinical Trials Registry Platform, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Wan-fang database, Chinese Scientific Journal Database, and other databases will be searched from establishment to April 1, 2018. All published randomized controlled trials (RCTs) about this topic will be included. Two independent researchers will operate article retrieval, screening, quality evaluation, and data analyses by Review Manager (V.5.3.5). Meta-analyses, subgroup analysis, and/or descriptive analysis will be performed based on included data conditions.
Results:
High-quality synthesis and/or descriptive analysis of current evidence will be provided from weight increase, motor development, neuropsychological development, length of stay, days of weight recovery to birthweight, days on supplemental oxygen, daily sleep duration, and side effects.
Conclusion:
This study will provide the evidence of whether pediatric Tuina is an effective early intervention for preterm infants.
Ethics And Dissemination:
There is no requirement of ethical approval and informed consent, and it will be in print or published by electronic copies.
Trail Registration Number:
This systematic review protocol has been registered in the PROSPERO network (No. CRD42018090563).
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