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Updated: Feb 11, 2026
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A Preclinical Murine Model of Hepatic Metastases
Published on: September 27, 2014
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Hepatic metastases from primary extremity leiomyosarcomas: Two case reports
Naoki Mizoshiri1, Toshiharu Shirai, Ryu Terauchi
1Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine Department of Pathology, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto, Kyoto, Japan.
Medicine
|May 3, 2018
Summary
Leiomyosarcoma, a rare cancer, can spread to the liver without lung metastasis. Regular CT scans are crucial for early detection of hepatic metastases in extremity leiomyosarcoma patients.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Leiomyosarcoma is a malignant soft tissue sarcoma with a propensity for metastasis.
- Lung metastasis is typical for extremity leiomyosarcomas, but hepatic involvement can occur.
Observation:
- Two cases of extremity leiomyosarcoma are presented, both with initial liver metastasis.
- Neither patient had evidence of lung metastasis at the time of hepatic lesion diagnosis.
Findings:
- Hepatic metastasis from extremity leiomyosarcoma can occur independently of lung metastasis.
- Surgical resection of primary tumors and subsequent hepatic metastases was performed in both cases.
Implications:
- Early detection of hepatic metastasis is vital for patient management.
- Periodic computed tomography (CT) scans of the chest and abdomen are recommended for surveillance.
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