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Echocardiographic evaluation of cardiac dyssynchrony: Does it still matter?
Donato Mele1, Giovanni Andrea Luisi1, Michele Malagù1
1Cardiology Unit and LTTA Center, University of Ferrara, Ferrara, Italy.
Insights
Cardiac resynchronization therapy (CRT) uses echocardiography to assess mechanical dyssynchrony in heart failure patients. This article clarifies the current role of mechanical dyssynchrony evaluation in selecting CRT candidates.
Area of Science:
- Cardiology
- Medical Imaging
- Heart Failure Management
Background:
- Cardiac resynchronization therapy (CRT) is a standard treatment for heart failure.
- Echocardiography-assessed cardiac mechanical dyssynchrony was historically key for CRT candidate selection.
- Current guidelines prioritize electrical dyssynchrony for CRT indications.
Purpose of the Study:
- To clarify the current utility of echocardiography in evaluating cardiac mechanical dyssynchrony.
- To determine the role of mechanical dyssynchrony assessment in contemporary CRT candidate selection and response prediction.
Main Methods:
- Review of current guidelines and literature on CRT indications.
- Analysis of echocardiographic parameters for assessing cardiac mechanical dyssynchrony.
- Discussion on the integration of mechanical dyssynchrony evaluation into clinical practice.
Main Results:
- Echocardiography remains a valuable tool for assessing cardiac mechanical dyssynchrony.
- Mechanical dyssynchrony evaluation provides complementary information beyond electrical criteria.
- Specific echocardiographic methods can effectively characterize dyssynchrony for CRT.
Conclusions:
- The evaluation of cardiac mechanical dyssynchrony by echocardiography remains relevant for optimizing CRT.
- Clinicians should consider mechanical dyssynchrony assessment alongside electrical criteria for comprehensive patient evaluation.
- Further research may refine the role of mechanical dyssynchrony in predicting CRT response.
Abstract:
Cardiac resynchronization therapy (CRT) is an established treatment for patients with heart failure and left ventricular systolic dysfunction. For many years, cardiac mechanical dyssynchrony assessed by echocardiography has been considered as a key evaluation to characterize CRT candidates and predict CRT response. In current guidelines, however, CRT implant indications rely only on electrical dyssynchrony. The aim of this article was to clarify whether and how the evaluation of cardiac mechanical dyssynchrony should be performed today by echocardiography.
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