Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Two-State Receptor Model01:29

The Two-State Receptor Model

3.1K
The two-state receptor model explains a drug's interaction with receptors, such as G protein-coupled receptors and ligand-gated ion channels, to induce or inhibit a biological response. When no natural ligands are present, a receptor exists in an equilibrium of inactive (Ri) and active (Ra) conformations. The inactive form does not produce a response, while the active form generates a basal effect known as constitutive activity.
The binding affinity of a drug determines its interaction with...
3.1K
Hybrid Zones02:29

Hybrid Zones

22.0K
Hybrid zones are narrow regions where two closely related species interact, mate, and produce hybrids. Relative to either parent species, hybrids may possess distinct phenotypic or genetic differences that impact their survival and reproductive success. The genetic variances introduced by hybridization influence species diversity and speciation processes within the hybrid zone.
22.0K
Hybridization of Atomic Orbitals I03:24

Hybridization of Atomic Orbitals I

67.7K
The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
67.7K
Hybridization of Atomic Orbitals II03:35

Hybridization of Atomic Orbitals II

49.2K
sp3d and sp3d 2 Hybridization
49.2K
Internal Receptors01:31

Internal Receptors

74.7K
Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
74.7K
Receptor-mediated Endocytosis01:39

Receptor-mediated Endocytosis

111.3K
Overview
111.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A dataset on morphology and composition of saltation-sandblasting dust particles from major Chinese source regions.

Scientific data·2026
Same author

Odor-Health Discrepancies in Urban Industrial Areas: Why TVOC Reduction Alone Fails to Mitigate Olfactory and Health Risks.

Environmental science & technology·2026
Same author

Rethinking Nitrate Aerosol Substitution for Sulfate in Winter Haze.

Environmental science & technology·2026
Same author

Global hotspots of particulate organic carbon losses under climate change.

Nature communications·2026
Same author

Unleashing the power of zero-valent platinum single atoms for enhancing low-temperature oxygen activation.

Nature communications·2026
Same author

Evaluation of real-time source apportionment approaches in six Chinese cities using the AXA (ACSM, Xact, Aethalometer) instrumental set-up.

Scientific reports·2026
Same journal

Friction-Mediated Transfer of Low Molecular Weight Chemicals from Consumer Mats to Fabrics: Insights for Dermal Exposure.

Environmental science & technology·2026
Same journal

Molecular Drivers of Contrasting Photoreactivity in Extracellular versus Intracellular Organic Matter from Chlorophyta and Cyanobacteria.

Environmental science & technology·2026
Same journal

Effective Precipitate Cleaning with a Reversible Flow Cell Sustains Stable Energy Intensity for Oceanic CO<sub>2</sub> Removal.

Environmental science & technology·2026
Same journal

The Efficiencies and Products of Dilute Methane Oxidation in a Chlorine Radical Photoreactor.

Environmental science & technology·2026
Same journal

Investigating Ultrafine Aerosol Turbulent Fluxes during Atmospheric New Particle Formation Events.

Environmental science & technology·2026
Same journal

Occurrence, Sources, and Export Rates of Ti-Bearing and Ce-Bearing (Nano)particles in the Seine River Where Engineered Nanoparticles Reach Natural Background Levels.

Environmental science & technology·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Double Whole Mount in situ Hybridization of Early Chick Embryos
15:42

Double Whole Mount in situ Hybridization of Early Chick Embryos

Published on: October 27, 2008

13.0K

PM2.5 Source Apportionment Using a Hybrid Environmental Receptor Model.

L-W Antony Chen1, Junji Cao2

  • 1Department of Environmental and Occupational Health, School of Community Health Sciences , University of Nevada , Las Vegas , Nevada 89154 , United States.

Environmental Science & Technology
|May 4, 2018
PubMed
Summary
This summary is machine-generated.

A new hybrid model combines chemical mass balance and positive matrix factorization for improved air pollution source apportionment. This tool enhances accuracy and uncertainty estimates, especially with partial source information.

More Related Videos

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
10:51

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

13.2K
Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization
06:00

Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization

Published on: August 27, 2021

6.1K

Related Experiment Videos

Last Updated: Feb 11, 2026

Double Whole Mount in situ Hybridization of Early Chick Embryos
15:42

Double Whole Mount in situ Hybridization of Early Chick Embryos

Published on: October 27, 2008

13.0K
Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
10:51

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 15, 2013

13.2K
Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization
06:00

Electroantennography-based Bio-hybrid Odor-detecting Drone using Silkmoth Antennae for Odor Source Localization

Published on: August 27, 2021

6.1K

Area of Science:

  • Environmental Science
  • Atmospheric Chemistry
  • Chemical Engineering

Background:

  • Accurate air pollution source apportionment is crucial for effective environmental management.
  • Existing models like Chemical Mass Balance (CMB) and Positive Matrix Factorization (PMF) have limitations in handling complex datasets and uncertainties.
  • The weight-of-evidence approach requires robust and integrated modeling techniques.

Purpose of the Study:

  • To develop and evaluate a hybrid environmental receptor model (HERM) integrating EV-CMB and PMF theories.
  • To enhance air pollution source apportionment by leveraging partial source information and improving uncertainty quantification.
  • To provide a user-friendly software tool for analyzing particulate matter (PM2.5) data.

Main Methods:

  • Development of a hybrid environmental receptor model (HERM) unifying EV-CMB and PMF.
  • Implementation of a software capable of single-run multi-sample EV-CMB analysis.
  • Utilizing partial source information to refine PMF rotational ambiguity and generate hybrid source profiles.
  • Testing HERM with simulated and real-world PM2.5 datasets.

Main Results:

  • HERM accurately reproduces EV-CMB results with improved tolerance to collinearity and better uncertainty estimates.
  • Partial source information effectively reduces PMF ambiguity, leading to more accurate source partitioning.
  • Hybrid mode source profiles are more representative of the study region compared to standalone models.
  • The software offers enhanced data input/output and analysis capabilities via MS Excel integration.

Conclusions:

  • The developed HERM provides a powerful and flexible tool for air pollution source apportionment.
  • Integrating EV-CMB and PMF theories with partial source information significantly improves apportionment accuracy and reliability.
  • HERM offers a valuable advancement for environmental agencies and researchers in understanding and managing air quality.