Scavenger receptor B type 1: expression, molecular regulation, and cholesterol transport function

Wen-Jun Shen1, Shailendra Asthana2, Fredric B Kraemer1

  • 1Geriatric Research, Education, and Clinical Research Center (GRECC), Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304 and Division of Endocrinology, Gerontology, and Metabolism, Stanford University School of Medicine, Stanford, CA 94305.

Summary

Scavenger receptor B type 1 (SR-B1) facilitates selective uptake of high-density lipoprotein cholesterol esters, crucial for cellular functions. Understanding SR-B1 regulation and variants may lead to new therapies for various diseases.

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