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Updated: Feb 11, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
[Cutaneous ulceration: metastases should be suspected]
Youssef Zemmez1, Badreddine Hassam1
1Service de Dermatologie, CHU Ibn Sina Rabat, Maroc.
A 68-year-old smoker presented with a chest wall mass and shortness of breath. Diagnosis was adenocarcinoma metastatic from lung cancer, with poor prognosis despite chemotherapy.
Area of Science:
- Oncology
- Pulmonology
- Dermatology
Background:
- Metastatic cancer can present with unusual cutaneous manifestations.
- Lung adenocarcinoma is a common malignancy with diverse presentations.
Observation:
- A 68-year-old chronic smoker developed a 5-month history of progressive, ulcerated chest wall swelling.
- Symptoms included worsening exertional dyspnea, general malaise, and significant weight loss.
- Physical examination revealed a 5cm x 5cm chest mass and bilateral axillary adenopathy.
Findings:
- Histopathology and immunohistochemistry confirmed cutaneous adenocarcinoma consistent with lung origin.
- Chest CT identified a left lingular pulmonary process.
Implications:
- This case highlights the importance of considering metastatic lung adenocarcinoma in patients with unexplained cutaneous lesions.
- Early diagnosis and appropriate staging are crucial for managing such advanced malignancies.
- The poor prognosis underscores the need for effective therapeutic strategies in metastatic lung cancer.
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