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Updated: Jul 16, 2026

Investigating Single Molecule Adhesion by Atomic Force Spectroscopy
Published on: February 27, 2015
A review of Winkler's foundation and its profound influence on adhesion and soft matter applications
David A Dillard1, Bikramjit Mukherjee, Preetika Karnal
1Biomedical Engineering and Mechanics Department, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA. dillard@vt.edu.
Abstract:
Few advanced mechanics of materials solutions have found broader and more enduring applications than Emil Winkler's beam on elastic foundation analysis, first published in 1867. Now, 150 years after its introduction, this concept continues to enjoy widespread use in its original application field of civil engineering, and has also had a profound effect on the field of adhesion mechanics, including for soft matter adhesion phenomena. A review of the model is presented with a focus on applications to adhesion science, highlighting classical works that utilize the model as well as recent usages that extend its scope. The special case of the behavior of plates on incompressible (e.g., elastomeric and viscous liquid) foundations is reviewed because of the significant relevance to the behavior of soft matter interlayers between one or more flexible adherends.
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