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Bioprinting of Hydrogel Tumor Slices as a 3D Model for Mantle Cell Lymphoma
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Electrochemical immunoassay for tumor markers based on hydrogels
1a Department of Chemistry , Capital Normal University , Beijing , China.
Expert Review of Molecular Diagnostics
|May 4, 2018
Summary
Hydrogel-based electrochemical immunoassays offer sensitive tumor marker detection due to their unique properties. Advances focus on functional hydrogels for improved biosensor performance.
Area of Science:
- Biomedical Engineering
- Materials Science
- Analytical Chemistry
Background:
- Hydrogels possess unique properties like high surface-to-volume ratio, biocompatibility, and stimuli-responsiveness.
- These properties make them ideal for sensitive and accurate detection of tumor markers.
- Electrochemical immunosensing techniques utilizing hydrogels have seen significant progress.
Purpose of the Study:
- To review recent advances in hydrogel-based electrochemical immunosensing interfaces for tumor markers.
- To highlight the diverse functions of hydrogels employed in these biosensors.
Main Methods:
- Review of literature on hydrogel-based electrochemical immunosensing for tumor markers.
- Categorization of hydrogels based on their functions: conductive, catalytic, redox, stimuli-responsive, and antifouling.
Main Results:
- Hydrogels have been successfully integrated into electrochemical immunoassays for tumor marker detection.
- Different functional hydrogels enhance the performance of electrochemical biosensors.
Conclusions:
- Hydrogel-based electrochemical biosensors show great potential for tumor marker detection.
- Further development requires fabricating novel hydrogels with enhanced and diverse functionalities.
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