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Updated: Feb 11, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Case for diagnosis. Multinucleated cell angiohistiocytoma
Margarida Rato1, Ana Filipe Monteiro1, Joana Parente1
1Hospital de Santarém EPE, Santarém, Portugal.
Abstract:
Multinucleate cell angiohistiocytoma is a rare idiopathic benign fibrohistiocytic and vascular proliferation usually presenting as multiple asymptomatic papules, red to violaceous in colour, primarily located on the extremities of middle-aged females. This entity is probably underdiagnosed due to the lack of recognition by clinicians and pathologists. We describe a patient with a multinucleate cell angiohistiocytoma of the face, a less frequent localization, in order to increase awareness of this entity and elucidate its clinical, histopathological, and immunohistochemistry features.
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