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Updated: Feb 11, 2026

Capsular Serotyping of Streptococcus pneumoniae by Latex Agglutination
Published on: September 25, 2014
[Latex-papaya syndrome: an infrequent association]
Victoria Rojas-Mandujano1, Kitzia González-Juárez, Cecilia Hernández-Fernández
1Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica. Ciudad de México, México. vickrojas.pedia@gmail.com.
Latex-papaya syndrome (LPS) involves papaya allergy in latex-allergic individuals, increasing anaphylaxis risk. Early diagnosis and patient education on adrenaline use are crucial for managing this severe condition.
Area of Science:
- Immunology
- Allergology
- Clinical Medicine
Background:
- Latex-fruit syndrome (LFS) links latex and plant allergies.
- Papaya contains potent allergens like papain and chitinases.
- Cross-reactivity between latex and papaya allergens may cause Latex-Papaya Syndrome (LPS).
Purpose of the Study:
- To detail the clinical presentation of patients diagnosed with LPS.
Main Methods:
- A cross-sectional, observational study included 11 patients with confirmed latex allergy and papaya-induced anaphylaxis.
- Diagnosis was based on skin prick tests and clinical history.
- Data were analyzed using descriptive statistics.
Main Results:
- 72.7% of LPS patients were female, aged 7-46.
- All patients experienced papaya-induced anaphylaxis.
- Risk factors included multiple surgeries, other allergies (food, medication, rhinitis, asthma), and healthcare employment.
- 63.3% showed anaphylaxis during skin prick testing.
Conclusions:
- Papaya hypersensitivity elevates anaphylaxis risk and mortality in latex-allergic patients.
- Clinical assessment is the primary diagnostic method for LPS.
- Patient education on anaphylaxis management, including adrenaline self-administration, is vital.
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