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[Plantago psyllium-secondary anaphylaxis. Case report].

Rodrigo Collado-Chagoya1, Javier Hernández-Romero, Gumaro Alejandro Eliosa-Alvarado

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Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|May 4, 2018
PubMed
Summary

Psyllium, a common laxative, can cause severe allergic reactions like anaphylaxis, even through inhalation. This case highlights the potential for life-threatening hypersensitivity to Plantago ovata derivatives.

Keywords:
Allergic reactionAnaphylaxisPsyllium

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Area of Science:

  • Allergy and Immunology
  • Pharmacology

Background:

  • Psyllium, derived from Plantago ovata, is widely used as a bulk-forming laxative due to its hydrocolloid properties.
  • While commonly ingested, psyllium exposure can occur via inhalation.

Observation:

  • A nurse experienced a severe anaphylactic reaction, including rhinoconjunctivitis, urticarial syndrome, angioedema, and bronchospasm, after preparing and administering a psyllium-based laxative.
  • The patient had a history of drug allergy and allergic rhinitis.

Findings:

  • Hypersensitivity to Plantago psyllium was confirmed through skin prick tests and specific IgE assays.
  • The reaction was severe despite exposure occurring solely through inhalation, not ingestion.

Implications:

  • This case underscores the potential for severe, life-threatening hypersensitivity reactions to psyllium, even with non-ingestive exposure routes.
  • Healthcare professionals should be aware of psyllium allergy risks, particularly in patients with pre-existing allergies.
  • Further investigation into psyllium's allergenic potential via different exposure routes is warranted.