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Complete Genome Sequence of a Streptococcus pyogenes Serotype M12 Scarlet Fever Outbreak Isolate from China, Compiled

Yuanhai You1, Yongjun Kou2, Longfei Niu2

  • 1State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

Genome Announcements
|May 5, 2018
PubMed

Insights

Scarlet fever remains a significant public health concern in China. This study presents the complete genome sequence of a Streptococcus pyogenes M12 isolate, the dominant serotype in recent outbreaks.

Area of Science:

  • Microbiology
  • Genomics
  • Epidemiology

Background:

  • Scarlet fever incidence is notably high in China.
  • Streptococcus pyogenes is the causative agent of scarlet fever.
  • Serotype M12 has been identified as predominant in recent outbreaks.

Purpose of the Study:

  • To report the complete genome sequence of a Streptococcus pyogenes M12 isolate.
  • To provide genomic data for understanding scarlet fever outbreaks in China.

Main Methods:

  • Whole genome sequencing was performed.
  • A combination of Oxford Nanopore MinION and Illumina sequencing technologies was utilized.

Main Results:

  • The complete genome sequence of a Streptococcus pyogenes M12 isolate was obtained.
  • This isolate represents the predominant serotype linked to recent scarlet fever outbreaks.

Conclusions:

  • The availability of this complete genome sequence aids in the genomic surveillance of Streptococcus pyogenes.
  • This data can contribute to understanding the epidemiology and evolution of scarlet fever in China.

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