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Updated: Feb 11, 2026

Direct Drug Delivery to Kidney via the Renal Artery
Published on: April 17, 2021
Renal artery aneurysm associated with Leber hereditary optic neuropathy
Ruth Ellen Jones1, Jessica Lee2, Mujtaba M Ali1
1Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Tex.
Abstract:
Leber hereditary optic neuropathy is an inherited, rare, mitochondrial metabolic disease that leads to progressive vision loss due to the accumulation of reactive oxygen species. The disorder has been associated with microangiopathy and macroangiopathy. We present a novel case of saccular left renal artery aneurysm in a 27-year-old man with known Leber hereditary optic neuropathy. The lesion was asymptomatic and grew from 1.8 to 2.0 cm during the course of 1 year. We successfully performed an endovascular left renal artery aneurysm repair.
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