Related Experiment Video
Updated: Feb 11, 2026
08:17
Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
Published on: June 7, 2015
16.2K
How Advances in Imaging Will Affect Precision Radiation Oncology
David A Jaffray1, Shiva Das1, Paula M Jacobs2
1Department of Medical Physics, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
Summary
Precision radiation oncology leverages advanced imaging and data analytics for personalized cancer treatment. Integrating diverse biomarkers and next-generation image-guided systems enhances therapeutic ratios and patient outcomes.
Area of Science:
- Medical Physics and Oncology
- Radiological Sciences
- Biomedical Engineering
Background:
- Radiation oncology is a highly technical medical discipline relying on advanced technology and digital approaches for cancer treatment.
- Accurate imaging is crucial for defining disease extent, heterogeneity, and proximity to normal tissues, directly impacting the therapeutic ratio.
- Image-based monitoring allows for treatment adaptation, improving efficacy and enabling better integration with other therapies like immunotherapy.
Purpose of the Study:
- To explore the potential and challenges of utilizing imaging data for personalized radiation therapy.
- To discuss the integration of multimodality predictions and patient-specific adaptations in radiation oncology.
- To highlight the role of emerging imaging technologies and biomarkers in optimizing cancer treatment.
Main Methods:
- Review of presentations and discussions from the 2016 American Society of Therapeutic Radiation Oncology-National Cancer Institute workshop on Precision Medicine in Radiation Oncology.
- Analysis of the integration of advanced imaging (CT, ultra-high-field MRI, molecular imaging) into radiation therapy planning and delivery.
- Consideration of diverse biomarkers, including tumor genomics, radiomics, tumor microenvironment analysis, and circulating tumor cells.
Main Results:
- Advanced imaging and data integration promise personalized radiation therapy pathways.
- Next-generation image-guided radiation therapy systems will enhance adaptive replanning capabilities.
- Combining pre- and peritherapeutic markers with imaging data is essential for maximizing patient benefit.
Conclusions:
- Exploiting imaging data is key to achieving personalized radiation therapy.
- Multimodality prediction and quantitative measures of treatment response will drive patient-specific adaptations.
- The integration of novel imaging technologies and biomarkers presents significant opportunities for advancing radiation oncology.
More Related Videos
06:37Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
Published on: October 20, 2010
23.8K
08:25Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
Published on: April 11, 2018
16.0K
Related Concept Videos
02:59Biological Effects of Radiation
18.1K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.1K
01:24Role of Affect in Interpersonal Attraction
235
Affect plays a crucial role in shaping interpersonal evaluations and perceptions. Emotions influence how individuals judge and respond to others, often determining whether interactions are viewed positively or negatively. This effect can manifest directly through interactions with the person in question or indirectly via associations with unrelated emotional experiences.Direct Effects of Affect on AttractionAffect directly influences interpersonal attraction when a person’s behavior...
235
01:29The Influence of Affect on Cognition
301
Positive affect significantly influences cognitive processes, including evaluation, memory, creativity, and social judgments. Compared to negative affect, positive emotional states promote more favorable interpretations of stimuli, cognitive flexibility, and heuristic processing. These effects highlight emotions' powerful role in shaping how individuals perceive, remember, and interact with the world.Influence on Evaluation and AttributionWhen individuals experience positive affect, they are...
301
01:29The Influence of Cognition on Affect
226
Cognition plays a pivotal role in shaping emotional experiences, as demonstrated by Schachter and Singer’s two-factor theory of emotion. According to this model, emotion arises from a combination of physiological arousal and cognitive interpretation. The body’s physiological response to stimuli is ambiguous and only gains emotional significance through cognitive labeling. For instance, an increased heart rate and adrenaline surge while standing near an attractive person may be...
226
01:17Radiation: Applications
1.8K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
The average...
1.8K
02:27Background and Environment Affect Phenotype
7.7K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
7.7K