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Electroconvulsive therapy (ECT) can lead to lasting improvements in mood and cognitive function for some patients. However, long-term cognitive stability after ECT varies, necessitating further research into predictive factors.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Electroconvulsive therapy (ECT) is a recognized treatment for severe mood disorders.
  • Long-term cognitive and psychological effects of ECT beyond one year are not well-documented.
  • Understanding sustained outcomes is crucial for patient management and treatment planning.

Purpose of the Study:

  • To evaluate long-term cognitive functioning, psychiatric symptoms, and quality of life in individuals after ECT.
  • To assess the stability of cognitive abilities and mood symptoms years post-treatment.
  • To identify potential predictors of sustained positive outcomes after ECT.

Main Methods:

  • A cohort of 294 participants with prior ECT underwent follow-up assessments.
  • A subsample (n=34) completed cognitive tests (RBANS, WAIS-IV), mood inventories (BDI-II, BAI), and quality of life measures.
  • Follow-up evaluations occurred an average of 6 years after the last ECT session.

Main Results:

  • Significant reductions in depressive symptoms (BDI-II scores) were observed.
  • Cognitive functioning, including memory and executive functions, remained largely stable.
  • A trend towards reduced visual-spatial scores (RBANS) was noted.
  • Improved mood correlated with better cognitive performance and quality of life.

Conclusions:

  • ECT may offer sustained benefits for mood and cognitive function in some individuals.
  • Cognitive stability and symptom reduction can persist for years post-ECT.
  • Findings are limited by selective participant sampling; further research is needed to identify predictors of long-term outcomes.