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Published on: September 11, 2018
Protocol incorporating airway CT decreases negative bronchoscopy rates for suspected foreign bodies in pediatric
Omar G Ahmed1, Robert P Guillerman2, Carla M Giannoni1
1Texas Children's Hospital, Otolaryngology, Houston, TEXAS, USA; Baylor College of Medicine, Otolaryngology, Houston, TEXAS, USA.
Insights
Selective low-dose computed tomography (CT) significantly reduces negative bronchoscopy rates in children with suspected foreign body aspiration (FBA). This imaging approach enhances diagnostic accuracy and lowers risks associated with unnecessary procedures.
Area of Science:
- Pediatric Pulmonology
- Medical Imaging
- Emergency Medicine
Background:
- Foreign body aspiration (FBA) is a critical cause of mortality in young children.
- Direct laryngoscopy and bronchoscopy (DL&B) is the standard diagnostic tool but has a high rate of negative findings.
- Unnecessary DL&B exposes children to significant operative, anesthetic, and financial risks.
Purpose of the Study:
- To evaluate the effectiveness of a clinical care protocol using low-dose non-contrast airway computed tomography (CT) in reducing negative bronchoscopy rates.
- To assess the diagnostic performance of airway CT in identifying pediatric airway foreign bodies.
Main Methods:
- Implementation of a clinical care protocol involving selective low-dose non-contrast airway CT for intermediate-risk FBA cases.
- Retrospective review comparing negative bronchoscopy rates before and after protocol implementation.
- Analysis of airway CT's diagnostic performance characteristics for foreign bodies.
Main Results:
- The negative bronchoscopy rate decreased from 37% to 17% after protocol implementation (p=0.06).
- Airway CT demonstrated high diagnostic accuracy: 91% sensitivity, 100% specificity, 100% positive predictive value, and 97% negative predictive value for foreign bodies.
Conclusions:
- Selective use of low-dose non-contrast airway CT in a clinical protocol effectively reduces negative bronchoscopy rates in children.
- This imaging strategy significantly lowers operative risks and healthcare costs associated with suspected FBA.
Background:
Foreign body aspiration (FBA) is the 4th leading cause of death in children between the ages 1-5. Although direct laryngoscopy and bronchoscopy (DL&B) is the reference standard for diagnosis of pediatric airway foreign bodies, there is a high negative bronchoscopy rate, exposing patients to unnecessary operative and anesthetic risks and costs.
Methods:
A clinical care protocol entailing the selective use of low-dose non-contrast airway computed tomography (CT) for children with an intermediate risk for FBA on the basis of clinical exam and chest radiography was implemented to decrease the negative DL&B rate. A retrospective review was conducted to compare negative bronchoscopy rates before and after implementation of the new protocol and the diagnostic performance characteristics of airway CT for airway foreign bodies were analyzed.
Results:
After implementation of the airway FB clinical care protocol entailing selective airway CT, the overall negative bronchoscopy rate decreased from an institutional historical rate of 37% (54/145) to 17% (10/56) (p = .06). The overall sensitivity, specificity, and positive and negative predictive value of airway CT for FB was 91%, 100%, 100%, and 97% respectively.
Conclusions:
Low-dose non-contrast airway CT is highly sensitive and specific for airway foreign bodies, and its selective use in a clinical care protocol for children with suspected foreign body aspiration could greatly reduce the negative bronchoscopy rate, thereby decreasing operative risks and costs.
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