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Synthesis of N-nicotinoyl-tryptamine (tryptamide)
M Eckstein1, S Misztal, A Terczyńska
1Department of Chemical Technology of Drugs, Academy of Sciences, Kraków, Poland.
Abstract:
N-Nicotinoyl-tryptamine was synthetized by acylation of tryptamine with mixed nicotinic anhydride. The synthesis of tryptamine via DL-tryptophan decarboxylation in cyclohexanol, in the presence of tetraline oxidation products as the catalyst, was described as well.