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Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression

Wenwen Liu1, Huan Wang2, Xiaokang Li1

  • 1Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Mei Long Road, Shanghai 200237, China.

Bioorganic & Medicinal Chemistry
|May 7, 2018
PubMed

Keywords:
5-HT reuptake inhibition5-HT(1A) agonistChE inhibitionCognitive impairmentDepressionMultitarget-directed ligand

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