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Updated: Feb 11, 2026

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Preparation of DNA-crosslinked Polyacrylamide Hydrogels
Published on: August 27, 2014
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Breastfeeding difficulty after polyacrylamide hydrogel (PAAG) mediated breast augmentation
Rami Mossad Ibrahim1, Elisabeth Lauritzen2, Caspar Weel Krammer3
1Department of Plastic Surgery, Herlev Hospital, Copenhagen, Denmark.
International Journal of Surgery Case Reports
|May 7, 2018
Summary
Polyacrylamide hydrogel (PAAG) breast augmentation can cause serious long-term issues, including infection and breastfeeding problems. Surgical removal of PAAG is necessary for treating these delayed complications.
Area of Science:
- Plastic Surgery
- Reconstructive Surgery
- Biomaterials Science
Background:
- Polyacrylamide hydrogel (PAAG) was a common material for minimally invasive breast augmentation.
- Increasing reports of complications associated with PAAG breast augmentation are emerging.
- This case highlights delayed infection and breastfeeding complications following PAAG augmentation.
Purpose of the Study:
- To report a case of delayed complications after PAAG breast augmentation.
- To emphasize the increasing prevalence of PAAG-related adverse events.
- To discuss the management of such complications.
Main Methods:
- A case study of a 36-year-old female with PAAG breast augmentation 15 years prior.
- Clinical evaluation, mammography, ultrasound, and MRI were used for diagnosis.
- Management involved aspiration, followed by modified radical debridement to remove PAAG.
Main Results:
- The patient presented with breastfeeding difficulty and a skin defect.
- Imaging revealed inhomogeneous gelatinous material (PAAG) diffused into breast tissue and muscle.
- Surgical removal of PAAG led to complete remission of infection and complications.
Conclusions:
- Complications from PAAG breast augmentation, including late infections and breastfeeding difficulties, are on the rise.
- PAAG can cause irreversible breast damage and necessitate complex surgical intervention.
- Effective management strategies are crucial for addressing long-term PAAG-related issues.
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