Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Membrane Proteins01:16

Introduction to Membrane Proteins

81.6K
The cell membrane, or plasma membrane, is an ever-changing landscape. It is described as a fluid mosaic where various macromolecules are embedded in the phospholipid bilayer. Among the macromolecules are proteins. The protein content varies across cell types. For example, mitochondrial inner membranes contain ~76% protein content, while myelin contains ~18% protein content. Individual cells contain many types of membrane proteins—red blood cells contain over 50—and different cell...
81.6K
The Resting Membrane Potential01:21

The Resting Membrane Potential

143.1K
Overview
143.1K
What are Membranes?01:54

What are Membranes?

192.5K
A key characteristic of life is the ability to separate the external environment from the internal space. To do this, cells have evolved semi-permeable membranes that regulate the passage of biological molecules. Additionally, the cell membrane defines a cell’s shape and interactions with the external environment. Eukaryotic cell membranes also serve to compartmentalize the internal space into organelles, including the endomembrane structures of the nucleus, endoplasmic reticulum and...
192.5K
What are Membranes?01:24

What are Membranes?

19.2K
A cell's plasma membrane demarcates the cell's borders and determines the nature of its interaction with the environment. Cells exclude certain substances, take in others, and excrete some others in controlled quantities. The plasma membrane must be flexible to allow certain cells, such as red and white blood cells, to change their shape while passing through narrow capillaries. These are the more obvious plasma membrane functions. In addition, the plasma membrane's surface carries...
19.2K
Membrane Proteins01:30

Membrane Proteins

30.6K
Plasma membranes have integral transmembrane proteins involved in facilitated transport. These proteins are collectively referred to as transport proteins, and they function as either channels for the material or as carriers themselves. Channel proteins have hydrophilic domains exposed to the intracellular and extracellular fluids and a hydrophilic channel through their core that provides a hydrated opening for solutes to pass through the membrane layers. Passage through the channel allows...
30.6K
Tissue Membranes01:27

Tissue Membranes

8.5K
A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
Connective Tissue Membranes
The connective tissue membrane is formed solely from connective tissue. These membranes encapsulate organs, such as the kidneys, and line our movable joints. A synovial...
8.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Year in review 2012: Critical Care--Nephrology.

Critical care (London, England)·2013
Same author

Healthcare systems and chronic kidney disease: putting the patient in control.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2013
Same author

Neutrophil gelatinase associated lipocalin in acute kidney injury.

Postgraduate medicine·2013
Same author

Ultrafiltration therapy for acute decompensated heart failure: lessons learned from 2 major trials.

American heart journal·2013
Same author

Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference.

Kidney international·2013
Same author

Association between renal replacement therapy in critically ill patients with severe acute kidney injury and mortality.

Journal of critical care·2013
Same journal

Beyond consent: community engagement, benefit sharing and reciprocity in kidney genomics research.

Nature reviews. Nephrology·2026
Same journal

The social needs of patients with kidney failure.

Nature reviews. Nephrology·2026
Same journal

Long-term kidney protection in IgA nephropathy with atrasentan.

Nature reviews. Nephrology·2026
Same journal

Benefits of finerenone treatment across chronic kidney disease aetiologies.

Nature reviews. Nephrology·2026
Same journal

The versatile roles of long non-coding RNAs in kidney disease.

Nature reviews. Nephrology·2026
Same journal

Sequential therapeutic approach for the management of osteoporosis in people with chronic kidney disease.

Nature reviews. Nephrology·2026
See all related articles

Related Experiment Video

Updated: Feb 11, 2026

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
22:00

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases

Published on: November 21, 2010

30.6K

Haemodialysis membranes.

Claudio Ronco1, William R Clark2

  • 1Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza, Italy.

Nature Reviews. Nephrology
|May 7, 2018
PubMed
Summary
This summary is machine-generated.

Advances in dialysis membrane technology require updated classifications beyond traditional flux and composition. New parameters like permeability indices and adsorption capacity are crucial for characterizing modern hemodialysis membranes.

More Related Videos

Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases
20:21

Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases

Published on: September 1, 2012

18.1K
A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
10:31

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics

Published on: September 2, 2020

8.1K

Related Experiment Videos

Last Updated: Feb 11, 2026

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
22:00

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases

Published on: November 21, 2010

30.6K
Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases
20:21

Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases

Published on: September 1, 2012

18.1K
A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
10:31

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics

Published on: September 2, 2020

8.1K

Area of Science:

  • Nephrology
  • Biomaterials Science
  • Extracorporeal Therapies

Background:

  • Hemodialysis utilizes semipermeable membranes to remove uremic toxins.
  • Traditional classification of dialysis membranes is based on composition and water permeability (low/high flux).
  • Material science advancements necessitate a re-evaluation of traditional membrane classification.

Purpose of the Study:

  • To provide clinicians with an updated analysis of dialysis membranes and dialyzers.
  • To discuss mechanisms of solute and water removal with highly permeable membranes.
  • To highlight advanced therapies like online hemodiafiltration and expanded hemodialysis.

Main Methods:

  • Review of current literature on dialysis membrane technology.
  • Analysis of solute and water removal mechanisms (diffusion, convection, adsorption, ultrafiltration).
  • Discussion of new parameters for membrane characterization (permeability indices, hydrophobicity, adsorption, electrical potential).

Main Results:

  • Newer membranes possess specific properties requiring advanced characterization beyond traditional metrics.
  • Highly permeable membranes enable advanced therapies like online hemodiafiltration.
  • Balancing large-solute clearance with albumin loss is a key consideration for extracorporeal therapies.

Conclusions:

  • Traditional dialysis membrane classification is insufficient for modern technologies.
  • Newer parameters are essential for characterizing advanced hemodialysis membranes.
  • Optimizing membrane properties is critical for effective and safe extracorporeal therapies, balancing efficacy with patient safety.